Penicillin Soup Recipe: When you’re feeling under the weather, nothing hits the spot quite like a bowl of warm, nourishing soup. One particular recipe that stands out during those sick days is Penicillin Soup—a nickname lovingly given to a powerful chicken soup that feels like medicine in a bowl. It’s not just comfort food; it’s the kind of meal that gives your body a fighting chance to bounce back. Whether you’re battling the flu, suffering from the sniffles, or just in need of something wholesome, this soup is your go-to remedy.
Nicknamed “Jewish Penicillin” because of its association with Jewish grandmothers and their famous chicken soup, this dish has taken on a near-mythical reputation. Why? Because it actually works. This is the kind of recipe that has been passed down through generations, tweaked lovingly by each family, and packed with ingredients that naturally help fight illness.
In this guide, we’re diving deep. You’ll get a full ingredient list, a detailed step-by-step cooking process, pro tips, alternatives, and even answers to common questions. Ready to turn your kitchen into a healing zone? Let’s get started.
What is Penicillin Soup?
Penicillin Soup is essentially a supercharged chicken soup, often enhanced with garlic, onions, herbs, and nutrient-rich vegetables. Think of it as chicken soup’s older, wiser cousin. It got its name because of its perceived healing powers—similar to how penicillin fights off infections. Jewish families especially have long referred to their traditional chicken soup as “Jewish Penicillin,” and for good reason.
The soup’s reputation isn’t just based on folklore. Studies have shown that chicken soup can help reduce upper respiratory inflammation and act as a mild decongestant. It’s rich in minerals and can be made even more potent with fresh herbs, spices, and aromatic vegetables. And let’s not forget—it’s just plain delicious.
Its warm, soothing broth coats the throat, its steam helps clear sinuses, and the combination of protein, vitamins, and minerals nourishes the body. The beauty of penicillin soup is that it’s not limited to a single culture anymore. Variations are found worldwide, each putting its own twist on this golden remedy.
Health Benefits of Penicillin Soup
Why is this soup so powerful? It’s all in the ingredients. Every component of penicillin soup plays a role in healing and nourishment. Let’s break down some of its main benefits:
- Boosts the immune system: Chicken provides zinc and iron, both vital for immune health. Garlic is a natural antimicrobial agent.
- Fights inflammation: Ginger, turmeric (if added), and garlic have anti-inflammatory properties that can reduce body aches and joint pain.
- Hydrates the body: The broth keeps you hydrated, which is especially important when you have a fever or are losing fluids through congestion.
- Clears the sinuses: The steam from hot soup helps relieve nasal congestion, and the warmth soothes sore throats.
- Promotes gut health: If you use homemade bone broth, it’s loaded with collagen and amino acids that promote digestive health.
This isn’t just food—it’s functional medicine in a bowl. And best of all, it tastes like home.
When Should You Eat Penicillin Soup?
While penicillin soup is typically a go-to during sick days, it’s actually great for many occasions. Think of it as your body’s best friend in the kitchen. Here are the best times to whip up a pot:
- During cold and flu season: The soup is packed with immune-boosting ingredients that help fight off viruses.
- After surgery or illness: It’s gentle on the stomach but loaded with nutrients, making it perfect for recovery.
- Post-workout recovery: Surprisingly, it can be a great way to refuel with protein and electrolytes.
- Daily or weekly immune support: Add it to your weekly meal prep during winter for ongoing wellness.
- When you’re feeling emotionally drained: Yes, soup can be soul food too. There’s something about it that lifts your spirits.
So whether it’s a sniffle or a soul that needs warming, penicillin soup has got you covered.
Ingredients You’ll Need
Here’s everything you need to make a hearty batch of penicillin soup. This list is flexible, so feel free to swap things based on what you have:
Main Ingredients:
- 1 whole chicken or 2 lbs chicken thighs (bone-in, skin-on for best flavor)
- 2 tablespoons olive oil
- 1 large onion, chopped
- 4-5 garlic cloves, minced
- 2 stalks celery, sliced
- 3 carrots, sliced
- 1 piece of fresh ginger (1-2 inches), grated
- 8 cups water or chicken broth
- 1 tablespoon apple cider vinegar (helps extract minerals from bones)
- 1 bay leaf
Herbs and Seasonings:
- 1 teaspoon thyme (fresh or dried)
- 1 teaspoon rosemary
- Salt and pepper to taste
- 1 bunch of fresh parsley (for garnish)
- Juice of ½ lemon (optional for brightness)
Optional Add-Ins:
- ½ teaspoon turmeric (for extra anti-inflammatory power)
- Noodles or rice (for more bulk)
- Mushrooms for added depth
With just these ingredients, you’re setting the stage for a flavorful, healing, and heartwarming soup.
Why These Ingredients Work
Ever wondered why these ingredients are more than just tasty? There’s a reason grandma’s soup always worked like magic. Each component in penicillin soup is like a natural medicine in its own right:
Chicken (with bones and skin)
Chicken provides protein, which is crucial for tissue repair and immune system support. But when you use bone-in pieces or a whole chicken, the magic multiplies. As the soup simmers, collagen and amino acids are released into the broth, which can help heal the gut lining and strengthen joints. The skin adds healthy fats that help with vitamin absorption.
Garlic, Onion, and Ginger
These three are a power trio when it comes to fighting off illness.
- Garlic contains allicin, a natural antimicrobial compound.
- Onions have quercetin, which supports respiratory health.
- Ginger helps soothe the stomach and fight inflammation.
Carrots and Celery
These veggies aren’t just here for color—they’re loaded with vitamins:
- Carrots give a boost of vitamin A, essential for immune function.
- Celery offers antioxidants and helps reduce inflammation.
Herbs: Thyme, Rosemary, Parsley
Herbs do more than flavor your soup—they act as natural medicine.
- Thyme has antiviral properties.
- Rosemary improves circulation and helps clear congestion.
- Parsley is rich in vitamin C and acts as a natural detoxifier.
Each ingredient plays its role in turning your soup into a well-rounded immune-boosting elixir. You’re not just eating—you’re fueling your body for recovery and strength.
Kitchen Tools You’ll Need
Before diving into the cooking process, make sure you have the right tools in place. Having a well-equipped kitchen can make a big difference in how smooth your cooking goes.
Must-Have Tools:
- Large soup pot or Dutch oven: A sturdy pot ensures even cooking and better heat retention.
- Sharp knife and cutting board: For prepping your vegetables and herbs.
- Ladle: For easy serving and tasting.
- Fine mesh strainer or skimmer: To remove foam or impurities from the top of the soup.
- Tongs or slotted spoon: To handle hot chicken pieces safely.
Optional but Helpful:
- Slow cooker or pressure cooker: For making the soup while you’re busy with other things.
- Soup storage containers: For freezing or refrigerating leftovers.
- Immersion blender: If you prefer a smooth soup texture or want to blend in some veggies for kids.
Having the right gear ready to go will save time and make the process less stressful—especially if you’re not feeling 100%.
Step-by-Step Guide to Making Penicillin Soup
Now we’re getting to the heart of it. Let’s walk through the complete, step-by-step process of making your own pot of penicillin soup at home. This is a classic stovetop version, but you can adapt it for a slow cooker or Instant Pot too.
Step 1: Prep Your Ingredients
Wash and chop all your vegetables (onion, garlic, carrots, celery, ginger). If using a whole chicken, rinse and pat it dry. For chicken pieces, leave the bones and skin on for deeper flavor.
Step 2: Sauté the Aromatics
In a large pot, heat 2 tablespoons of olive oil over medium heat. Add the chopped onions and sauté until they become translucent—about 5 minutes. Add garlic, ginger, and celery, and stir for another 2 minutes.
This step unlocks the flavors of your base and gives the soup depth.
Step 3: Add Chicken and Broth
Place your whole chicken or pieces into the pot. Pour in 8 cups of water or low-sodium chicken broth. Add apple cider vinegar, which helps pull nutrients from the chicken bones into the broth.
Bring to a gentle boil, then immediately reduce the heat to low. Skim off any foam that rises to the surface with a spoon or skimmer.
Step 4: Simmer Low and Slow
Add carrots, herbs (thyme, rosemary, bay leaf), and a generous pinch of salt and pepper. Cover the pot partially and let it simmer on low heat for 90 minutes to 2 hours. The longer, the better—the flavors develop beautifully over time.
If using a whole chicken, carefully remove it after about 90 minutes, shred the meat, discard the bones, and return the meat to the pot.
Step 5: Final Touches
Taste your broth. Adjust with more salt, pepper, or a squeeze of lemon juice for brightness. Add fresh parsley at the very end to lock in that green freshness.
Want noodles or rice? Add them in the last 10–15 minutes so they don’t overcook.
That’s it! You’ve got a pot of comforting, healing penicillin soup ready to go.
Pro Tips for the Best Flavor
Want to take your soup from good to great? These kitchen hacks will elevate every spoonful.
1. Roast Your Chicken First
For an even deeper, richer flavor, roast your chicken (or chicken parts) at 400°F for 30–40 minutes before adding to the soup pot. The caramelization adds a savory umami kick you won’t believe.
2. Add a Splash of Vinegar or Lemon
A dash of apple cider vinegar during cooking pulls out nutrients from bones. At the end, a squeeze of fresh lemon juice brightens the entire dish, making flavors pop.
3. Use Fresh Herbs Over Dried
Fresh herbs like thyme and rosemary give a more vibrant taste. Add them toward the end of cooking so they don’t lose their oils and potency.
4. Let It Rest
If you can resist diving in right away, let the soup rest for 10–15 minutes after cooking. This helps all the flavors blend together even more.
These tiny details can turn a simple soup into a standout dish that heals, comforts, and satisfies.
How to Make It Vegetarian or Vegan
Want the healing benefits of Penicillin Soup without the meat? No problem. This soup adapts beautifully into a vegetarian or even vegan-friendly version while still delivering on flavor and nutrition. You’ll just need to make a few smart swaps.
1. Replace the Chicken
Instead of chicken, use hearty plant-based proteins like:
- Chickpeas or white beans – great for protein and texture.
- Tofu or tempeh – marinate and pan-fry them before adding.
- Mushrooms – especially shiitake or cremini for a meaty umami depth.
2. Use Vegetable Broth
Go for a rich, homemade vegetable broth, or choose a high-quality store-bought option. Add in some kombu (seaweed) or miso paste to enhance the flavor naturally.
3. Double Down on Veggies
Since you’re skipping the chicken, boost the nutritional power with:
- Sweet potatoes or squash for body and vitamins
- Spinach, kale, or chard for added iron and antioxidants
- Extra garlic and ginger for stronger immune support
4. Don’t Forget the Fat
To mimic the richness of chicken soup, use olive oil, coconut oil, or even a small amount of plant-based butter to give the soup a comforting mouthfeel.
Even without animal products, this version still delivers that soul-warming comfort, helping you feel better from the inside out.
Storing and Reheating Penicillin Soup
One of the best things about this soup? It tastes even better the next day. Here’s how to store and reheat it properly so you can enjoy it anytime.
Storage Tips:
- In the fridge: Let the soup cool completely. Store it in an airtight container for up to 5 days.
- In the freezer: Pour cooled soup into freezer-safe containers or zip-top bags (leave space for expansion). Freeze for up to 3 months.
For best results, store in individual portions so you can reheat just what you need.
Reheating Tips:
- Stovetop: Pour into a saucepan and heat over medium until simmering.
- Microwave: Reheat in microwave-safe containers in 1-minute intervals, stirring between each.
- From frozen: Defrost overnight in the fridge or run under warm water to loosen, then reheat on the stove.
Remember, if you added rice or noodles, they may absorb more liquid. You might need to add a splash of water or broth when reheating to loosen the consistency.
Serving Suggestions
Penicillin Soup is delicious on its own, but the right sides and toppings can turn it into a full meal or even a dinner party centerpiece.
1. With Bread
- Crusty sourdough or baguette slices make perfect dippers.
- Add garlic butter toast for even more flavor.
2. With Rice or Noodles
- A scoop of steamed jasmine rice or egg noodles turns this soup into a hearty main.
- Try orzo or quinoa for a healthier twist.
3. Garnish Game Strong
- Fresh parsley, dill, or chopped green onion adds freshness.
- A sprinkle of chili flakes or a swirl of olive oil enhances depth.
4. Pair with a Side Salad
- A simple mixed greens salad with lemon vinaigrette keeps the meal light.
- Or try a cucumber and tomato salad with fresh herbs to brighten the palate.
Serve it in big bowls, with a blanket on your lap, and you’ve got the ultimate cozy meal.
Kids and Penicillin Soup
Let’s face it—kids can be picky. But Penicillin Soup can be made super kid-friendly with just a few small adjustments, making it a go-to for busy parents.
Make It Mild
- Go light on the garlic and ginger if your child isn’t used to bold flavors.
- Skip chili or strong spices—save those for adult servings.
Shred or Dice Chicken Small
Kids are more likely to eat chicken if it’s soft and in small pieces. Bonus: it’s safer and easier for toddlers too.
Blend the Veggies
If your kiddo won’t touch carrots or celery, try blending the soup into a smooth purée. You can sneak in the nutrition without the fuss.
Add Fun Shapes
Add fun-shaped pasta like stars, letters, or animals to make it more visually appealing.
Penicillin Soup doesn’t just nourish—it brings comfort. And when your child is feeling sick or fussy, this is a dish that’ll soothe from the inside out.
Common Mistakes to Avoid
Even a simple soup can go wrong if you’re not careful. Here’s what to watch for when making Penicillin Soup:
1. Overcooking the Vegetables
No one likes mushy carrots or celery. Add the vegetables after the soup has simmered for a while or keep them chunky so they hold up better.
2. Using Boneless, Skinless Chicken Breast
This will make your soup bland and dry. Always opt for bone-in, skin-on chicken for maximum flavor and richness.
3. Not Skimming the Fat or Foam
During the first boil, chicken releases foam. Skim this off for a clearer, cleaner-tasting broth.
4. Overseasoning Early
Soup reduces over time, so if you add salt too early, it can become too salty. Wait until the end to adjust the seasoning.
5. Not Simmering Long Enough
This isn’t fast food. Let the soup simmer low and slow for at least 90 minutes to build deep, layered flavors.
Avoiding these mistakes ensures your penicillin soup isn’t just good—it’s heaven in a bowl.
FAQs about Penicillin Soup Recipe
1. Can I make this in a slow cooker?
Absolutely. Just add all ingredients to the slow cooker and cook on low for 6–8 hours or high for 4 hours. Shred the chicken and return it to the pot before serving.
2. Is Penicillin Soup good for digestion?
Yes! Especially if made with bone-in chicken or bone broth, it provides gelatin and collagen that support gut health.
3. How long should I simmer it?
Aim for 90 minutes to 2 hours for the richest flavor and best nutrient extraction.
4. Can I freeze it in individual portions?
Definitely. Use freezer-safe containers or silicone soup molds to freeze in portions for quick and easy reheating.
5. What can I use instead of chicken?
For a vegetarian version, try mushrooms, beans, or tofu. Use veggie broth and amp up the garlic, ginger, and herbs for depth.
Conclusion
Penicillin Soup isn’t just another chicken soup recipe—it’s the culinary equivalent of a warm hug. Packed with healing herbs, immune-boosting ingredients, and slow-simmered comfort, this soup has rightfully earned its reputation as the “natural antibiotic.”
Whether you’re fending off a winter bug, feeding your family, or just craving a taste of home, this soup delivers every time. And the best part? It’s customizable, easy to make in big batches, and stores beautifully.
So next time you feel a scratch in your throat or a chill in the air, don’t reach for a pill—reach for a pot. Let Penicillin Soup do what it does best: heal, nourish, and comfort.
